My Alopecia Journey

  FOXN1 is  a gene that encodes a transcription factor crucial for the development of the thymus, skin, hair, and nails , and mutations in this gene can lead to severe combined immunodeficiency (SCID) and other conditions.   Here's a more detailed explanation: Function of FOXN1:  Transcription Factor: FOXN1 is a protein that acts as a transcription factor, meaning it regulates the activity of other genes by binding to specific DNA regions.   Thymus Development: FOXN1 plays a vital role in the development of the thymus, an organ where T cells (a type of immune cell) mature.   Skin, Hair, and Nail Development: FOXN1 is also involved in the development and function of skin, hair follicles, and nail beds.   Master regulator of TECs: FOXN1 is a master regulator of thymic epithelial cells (TECs) and is required for the development of these cells in the thymus, skin, hair and nails.   FOXN1 Deficiency and Associated Conditions:  Severe Combined Immu...

  So another week on Litfulo and so far so good.   Had a bit of heartburn but  I have had that in the past so probably just a coincidence.  Been researching alopecia and found out there is actually a genetic test you can have. The details below are from google search very interesting reading  Dare to dream xxxx

 A lot of people are asking about eyebrows. I had tattoos and it made me feel more confident. Also people ask how long they last. I had mine done 2 years ago you can still see them. I would highly having them and I am happy I share the wonderful lady who did mine xxxx

  Hi So I have been getting a lot of messages asking about the process and tests you need to be able to start Litfulo.  Here is my story.  I have been with dermatology for over 10 years for both alopecia and eczema.  Last year when I heard about the treatment I emailed my dermatologist and was put on the list, she advised me it was still waiting approval from National Institute for Health and Care Excellence (NICE) in my local area (Derbyshire) and I was put on the waiting list in April 2024.  I never thought it would actually happen but on 26/112024 I got a letter with an appointment for 05/03/2024.  I couldn’t wait.  I was unsure what the initial tests would involve but as a nurse I looked it up and knew I needed bloods and x-rays.  The day of the appointment came and I was so excited. I only had to wait 5 minutes and was taken into a room where my height, weight and blood pressure was taken. They also took numerous blood tests for    ...

So I have been taking Litfulo for 7 days and so far not had any real side affects other than a slight tummy ache which lasted less than 10 minutes so I can cope with that. I am also sleeping really well which I never do, this could just be a coincidence but who knows it’s early days. I have met online some lovely people who are also suffering with alopecia some having treatment and some awaiting input, feel free to share your stories in the comments section as alopecia is real and nothing to be ashamed of.  I may be imagining things but I am convinced I have some fluff but I suppose it is too early to say if it’s working or not.  I will post some pictures over the weekend as taking pictures of the back of your head is difficult 😂  Anyway all peace and love can’t wait to hear from you all Dare to dream xxxx  

 23rd March 2025 So far so good started the tablets on the 19th. So far I have not noticed any side effects and I am feeling hopeful.  I take the tablet in the morning and do not take it with food and no nausea or anything like that so far. I may be dreaming but I’m convinced I have some hair growth.  Dare to dream xxxx

 

 

 Not many people understand how much alopecia takes from you. In 2015 I lost all my hair and then a few years later I lost my eyebrows and eyelashes which was so devastating.  I have been to many specialists and tried every treatment available but nothing has worked.  Last year a drug was found which works for alopecia and I have been waiting until I can start taking it. Last week I finally completed all the tests and was prescribed the treatment Litfulo (ritlecitinib). I started the tablets last week and I am going to document my progress. I will post pictures of my head once a month and will keep a weekly blog diary to let you all know how I am managing the medication and any side effects.  Wish me luck  Love to you all  xxxx